Three-component coupling synthesis of pr
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Masaaki Suzuki; Yasushi Morita; Hiroshi Koyano; Masahiro Koga; Ryoji Noyori
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Article
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1990
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Elsevier Science
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French
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In the presence of dtmethylzinc. (R)-tert-butyldimethylstloxy-2cyclopentenone can be linked with (S.E)-1-lithio-3-tert-butyldimethylsiloxy-1 -octene and methyl 7-iodo-5-heptynoate. giving a protected 5,6didehydroprostaglandin E2. Use of an o side-chain aldehyde or nitroalkene in place of the propar