The inheritance of pyloric stenosis is explained by a multifactorial threshold model with an underlying assumption that the liability for the disease is distributed in males and females showing a sex dimorphism. From the available data on familial occurrences of pyloric stenosis, it is shown, that a
A General Statistical Model for Multifactorial Inheritance of Discontinuous Traits
โ Scribed by D. G. Bonet; Susan I. Smalley; J. A. Woodward
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 445 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0323-3847
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โฆ Synopsis
Angel-r9ummary
A general etstiatioal model for the analysis of ordered discrete phenotypee given a multifaotoriel mode of inheritance ie outlined. This model oan be applied to give (i) a0mponent.a of varianoe and ooverianoe for vmioue genetio and environmentel effwtn that 810 eatimable from the genetio sampling deeign, (ii) a faotor analysia atruoture, and (iii) regreseion eetimatee for deeoription of the relationehip among the genetio and environmentel fectom.
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