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A general method to modify BACs to generate large recombinant DNA fragments

✍ Scribed by Wei Shen; Yue Huang; Yi Tang; De-Pei Liu; Chih-Chuan Liang

Book ID
111640496
Publisher
Humana Press Inc
Year
2005
Tongue
English
Weight
231 KB
Volume
31
Category
Article
ISSN
1073-6085

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Several whole genome amplification strategies have been developed to preamplify the entire genome from minimal amounts of DNA for subsequent molecular genetic analysis. However, none of these techniques has proven to amplify long products from very low (nanogram or picogram) quantities of genomic DN