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A General Method for the Synthesis of 2-Azetidinones and 2-Azetidinylideneammonium Salts

✍ Scribed by Dr. Michel De Poortere; Dr. Jacqueline Marchand-Brynaert; Prof. Léon Ghosez


Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
207 KB
Volume
13
Category
Article
ISSN
0044-8249

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An efficient, three-step synthesis of N-vinyl-2-azetidinones 7 selenylation, and finally m-CPBA treatment, afforded Nvinyl-2-azetidinones 7 in fair to excellent yields, with starting from αor β-amino ester imines 4 has been developed. Staudinger reaction between imines 4 and a retention at the remai