A general approach to selection of multiple cubic volume elements using the ISIS technique
✍ Scribed by R. J. Ordidge; R. M. Bowley; G. McHale
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 538 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
The ISIS method is used regularly for the selection of a single cubic volume of tissue for in vivo investigation by high-resolution NMR spectroscopy. This technique has been extended on a theoretical basis to include the simultaneous selection of a number of cubes, the signals from which can be either assessed individually or in certain circumstances coadded to produce improvement in signal-to-noise ratio. The modification requires additional selective RF pulses in the spatial encoding prepulse period, and spatially localized spectra are produced by addition and subtraction of NMR signals in a manner similar to the original ISIS technique.