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A General and Regioselective Synthesis of 5-Trifluoromethyl-pyrazoles

✍ Scribed by Foster, Robert S.; Jakobi, Harald; Harrity, Joseph P. A.

Book ID
120014791
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
465 KB
Volume
14
Category
Article
ISSN
1523-7060

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✍ Marcos A. P. Martins; Claudio M. P. Pereira; Sidnei Moura; Clarissa P. Frizzo; P 📂 Article 📅 2007 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 311 KB

## Abstract magnified image The regiospecific synthesis of a series of twelve 5‐trifluoromethyl‐4,5‐dihydropyrazoles and ‐pyrazoles from the cyclocondesation reaction of 4‐alkoxy‐1,1,1‐trifluoro‐3‐alken‐2‐ones [F~3~CC(O)CH=C(R^1^)OR, where R^1^ = Me, Et, Pr, __iso__‐Pr, Bu, iso‐Bu, Ph, H; and R =