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A Gene for an Autosomal Dominant Scleroatrophic Syndrome Predisposing to Skin Cancer (Huriez Syndrome) Maps to Chromosome 4q23

✍ Scribed by Young-Ae Lee; Howard P. Stevens; Emmanuel Delaporte; Ulrich Wahn; André Reis


Book ID
117853122
Publisher
American Society of Human Genetics
Year
2000
Tongue
English
Weight
127 KB
Volume
66
Category
Article
ISSN
0002-9297

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Hidrotic ectodermal dysplasia (HED), Clouston syndrome (MIM No. 129500), is an autosomal dominant disorder affecting the skin and its derivatives. It is characterized by alopecia, dysplastic nails in hands and feet, and hyperkeratosis of the palms and soles. We have studied a large Indian pedigree (