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A gene cluster of the ochratoxin A biosynthetic genes inPenicillium

✍ Scribed by R. Geisen; M. Schmidt-Heydt; A. Karolewiez


Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
736 KB
Volume
22
Category
Article
ISSN
0178-7888

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Two overlapping cosmid clones (Cos1-1 and Cos9-1) carrying the Tox5 gene were isolated from a library of F. sporotrichioides strain NRRL 3299 genomic DNA. These cosmids were used to transform three T-2 toxin-deficient mutants that are blocked at different steps in the trichothecene pathway. Both cos