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A GATA binding site is involved in the regulation of 15-lipoxygenase-1 expression in human colorectal carcinoma cell line, Caco-2

✍ Scribed by Hideki Kamitani; Hideto Kameda; Uddhav P. Kelavkar; Thomas E. Eling


Book ID
117101477
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
291 KB
Volume
467
Category
Article
ISSN
0014-5793

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## Abstract Angiopoietins are ligands of the endothelial cell tyrosine kinase receptor Tie2. Angiopoietin‐1 (Ang‐1) is widely expressed in human normal adult tissues and promotes blood vessel maturation and stabilization by inducing Tie2 receptor phosphorylation. In contrast, the antagonistic ligan