A functional variant provided further evidence for the association of ARVCF with schizophrenia
✍ Scribed by Sergi Mas; Miquel Bernardo; Patricia Gassó; Santi Álvarez; Clemente Garcia-Rizo; Miquel Bioque; Brian Kirkpatrick; Amalia Lafuente
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 144 KB
- Volume
- 9999B
- Category
- Article
- ISSN
- 1552-4841
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Dopamine -hydroxylase (DBH), the enzyme that converts dopamine to norepinepherine, has been proposed as being involved in the aetiology of schizophrenia. Previous work identified a functional polymorphism at nucleotide 910 of the DBH gene that results in a codon change in the mature protein Ala304S
## Abstract Multiple studies have reported an association between attention deficit hyperactivity disorder (ADHD) and the 10‐repeat allele of a variable number tandem repeat (VNTR) polymorphism in the 3′‐untranslated region (3′UTR) of the dopamine transporter gene (__DAT1__). Yet, recent meta‐analy