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A functional variant in FCRL3 is associated with higher Fc receptor–like 3 expression on T cell subsets and rheumatoid arthritis disease activity

✍ Scribed by Urmila D. Bajpai; Louise A. Swainson; Jeff E. Mold; Jonathan D. Graf; John B. Imboden; Joseph M. McCune

Book ID: 112002745
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 281 KB
Volume: 64
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.34457

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## Abstract ## Objective Fcγ receptors (FcγRs) recognize immune complexes (ICs) and coordinate the immune response by modulating the functions of dendritic cells (DCs). The purpose of this study was to unravel the role of the inhibitory FcγRIIb in rheumatoid arthritis (RA) by studying the effect o