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A functional SNP in the NKX2.5-binding site ofITPR3promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population

✍ Scribed by Tetsuya Oishi; Aritoshi Iida; Shigeru Otsubo; Yoichiro Kamatani; Masayuki Usami; Takashi Takei; Keiko Uchida; Ken Tsuchiya; Susumu Saito; Yozo Ohnisi; Katsushi Tokunaga; Kosaku Nitta; Yasushi Kawaguchi; Naoyuki Kamatani; Yuta Kochi; Kenichi Shimane; Kazuhiko Yamamoto; Yusuke Nakamura; Wako Yumura; Koichi Matsuda

Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 422 KB
Volume: 53
Category: Article
ISSN: 1435-232X
DOI: 10.1007/s10038-007-0233-3

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## Abstract ## Objective In Japanese individuals, the −169C/T single‐nucleotide polymorphism (SNP) in __FCRL3__ has been reported to be associated with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and autoimmune thyroid diseases. The objective of this study was to test the associ