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A functional polymorphism (Ser326Cys) of the human 8-oxoguanine DNA glycosylase (hOGG1) gene and schizophrenia

✍ Scribed by Shinichi Sakata; Takahiro Shinkai; Rudi Hwang; Kensuke Utsunomiya; Kenji Yamada; Hsin-I Chen; Osamu Ohmori; Jun Nakamura

Book ID
116850033
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
97 KB
Volume
177
Category
Article
ISSN
0165-1781

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Ser326Cys polymorphism in hOGG1 gene and
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Ser326Cys polymorphism in the hOGG1 gene, which is involved in the repair of 8-hydroxyguanine in oxidatively damaged DNA, has been identified and the variant genotype appears to be related to susceptibility to certain cancers. We investigated the association between Ser326Cys polymorphism and squamo