## Abstract ## Objective Lupus nephritis (LN) is a major contributor to morbidity and mortality in patients with systemic lupus erythematosus (SLE). There is evidence that polymorphisms in the genes of inflammatory mediators may predispose to the development of LN in patients with SLE. In this stu
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A functional polymorphic variant in the interleukin-6 gene promoter associated with low bone resorption in postmenopausal women
โ Scribed by S. L. Ferrari; P. Garnero; S. Emond; H. Montgomery; S. E. Humphries; S. L. Greenspan
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 126 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0004-3591
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A commonly occurring sequence variant in the islet-specific promoter of the glucokinase gene (-30 G to A) has been variably reported to be associated with reduced insulin secretory responses to oral glucose. The effect of this promoter variant may be subtle and only become apparent under conditions