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A functional interferon regulatory factor-1 (IRF-1)-binding site in the upstream regulatory region (URR) of human papillomavirus type 16

✍ Scribed by Istvan Arany; Kenneth J Grattendick; William E Whitehead; Istvan A Ember; Stephen K Tyring

Book ID: 114093116
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 197 KB
Volume: 310
Category: Article
ISSN: 0042-6822
DOI: 10.1016/s0042-6822(03)00138-7

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## Abstract Human papillomavirus type‐16 (HPV‐16) is an epitheliotropic DNA tumor virus associated with the development of cervical carcinoma. The expression of HPV‐16 early genes is driven by a cell‐type—specific enhancer located in the long control region of the viral genome. We identified an ele