In studying decline among cognitively impaired people, a prevalent cohort study design is commonly used to account for entry into the study at di erent levels of impairment. The data set typically consists of many short series of repeated measurements collected over time. However, the time origin, s
β¦ LIBER β¦
A FUNCTIONAL DECLINE MODEL FOR PREVALENT COHORT DATA
β Scribed by XINHUA LIU; WEI-YANN TSAI; YAAKOV STERN
- Book ID
- 102650281
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 562 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0277-6715
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β¦ Synopsis
Longitudinal designs are often used for studying the natural history of diseases. Data sets typically consist of short series of repeated measures on prevalent cases. We propose a growth model approach to the analysis of follow-up data to describe functional decline and associated risk factors in disease progression. We illustrate the model with an application to longitudinal data that describe the time-evolution of cognitive decline in a cohort of patients with Alzheimer's disease.
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