In order to analyze the mutational events and to understand the biological significance of the p53 gene in chemical carcinogenesis, we applied a new yeast-based p53 functional assay to ovarian tumors induced by 7, 12-dimethylbenz[a]anthracene (DMBA), as well as to transitional cell carcinomas of the
A functional and quantitative mutational analysis of p53 mutations in yeast indicates strand biases and different roles of mutations in DMBA- and BBN-induced tumors in rats
โ Scribed by K. Yamamoto; D. Nakata; M. Tada; H. Tonoki; T. Nishida; A. Hirai; Y. Ba; T. Aoyama; J.-I. Hamada; K. Furuuchi; H. Harada; K. Hirai; N. Shibahara; Y. Katsuoka; T. Moriuchi
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 9 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0020-7136
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