The extent of neurogenesis in Drosophila is under the control of the so-called neurogenic genes, named for their mutant phenotype of causing neural hyperplasia. Their wild-type products appear to be responsible for a signal chain that decides the fate of ectodermal cells in the embryo. Various kinds
✦ LIBER ✦
A functional analysis of the genes Enhancer of split and HLH-m5 during early neurogenesis in Drosophila melanogaster
✍ Scribed by Tietze, Kyria ;Schrons, Herbert ;Campos-Ortega, Jos� A. ;Knust, Elisabeth
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 928 KB
- Volume
- 203
- Category
- Article
- ISSN
- 1432-041X
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## Abstract Insulin‐like growth factor‐1 (IGF‐1) is essential to hippocampal neurogenesis and the neuronal response to hypoxia/ischemia injury. IGF (IGF‐1 and ‐2) signaling is mediated primarily by the type 1 IGF receptor (IGF‐1R) and modulated by six high‐affinity binding proteins (IGFBP) and the