An amplified NS0 cell line transfected with a vector expressing a humanized monoclonal antibody (MAb) against CD-18 and glutamine synthetase (GS) was cultivated in a 1.5 L fed-batch culture using a serum-free, glutamine-free medium. Concentrated solutions of key nutrient components were fed periodic
A fully defined, fed-batch, recombinant NS0 culture process for monoclonal antibody production
โ Scribed by Paul A. Hermes; Chris D. Castro
- Publisher
- American Institute of Chemical Engineers
- Year
- 2010
- Tongue
- English
- Weight
- 237 KB
- Volume
- 26
- Category
- Article
- ISSN
- 8756-7938
- DOI
- 10.1002/btpr.455
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