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A fully automated multicapillary electrophoresis device for DNA analysis

✍ Scribed by Sven Behr; Martin Mätzig; Alexander Levin; Holger Eickhoff; Christoph Heller

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 601 KB
Volume: 20
Category: Article
ISSN: 0173-0835
DOI: 10.1002/(sici)1522-2683(19990601)20:7<1492::aid-elps1492>3.0.co;2-v

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✦ Synopsis

We describe the construction and performance of a fully automated multicapillary electrophoresis system for the analysis of fluorescently labeled biomolecules. A special detection system allows the simultaneous spectral analysis of all 96 capillaries. The main features are true parallel detection without any moving parts, high robustness, and full compatibility to existing protocols. The device can process up to 40 microtiter plates (96 and 384 well) without human interference, which means up to 15,000 samples before it has to be reloaded.

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