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A Free-Running DNA Motor Powered by a Nicking Enzyme

โœ Scribed by Jonathan Bath; Simon J. Green; Andrew J. Turberfield


Book ID
101532801
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
318 KB
Volume
117
Category
Article
ISSN
0044-8249

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A Free-Running DNA Motor Powered by a Ni
โœ Jonathan Bath; Simon J. Green; Andrew J. Turberfield ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 318 KB

Herein, we present a simple linear motor, built from DNA and a restriction enzyme, which moves a DNA cargo in discrete steps along a DNA track. Movement is powered by a nicking enzyme that cuts the track. Damage to the track in the wake of the cargo imposes directionality. The specificity of base-p