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A framework for cost-effectiveness analysis from clinical trial data

✍ Scribed by Anthony O'Hagan; John W. Stevens

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 262 KB
Volume: 10
Category: Article
ISSN: 1057-9230
DOI: 10.1002/hec.617

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We present a general Bayesian framework for cost‐effectiveness analysis (CEA) from clinical trial data. This framework allows for very flexible modelling of both cost and efficacy related trial data. A common CEA technique is established for this wide class of models through linking mean efficacy and mean cost to the parameters of any given model.

Examples are given in which efficacy may be measured as a continuous, binary, ordinal or time‐to‐event outcome, and in which costs are modelled as distributed normally, log‐normally, as a mixture or non‐parametrically.

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