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A Frailty Mixture Cure Model with Application to Hospital Readmission Cata

✍ Scribed by Binbing Yu


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
114 KB
Volume
50
Category
Article
ISSN
0323-3847

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✦ Synopsis


Abstract

Mixture cure models have been utilized to analyze survival data with possible cure. This paper considers the inclusion of frailty into the mixture cure model to model recurrent event data with a cure fraction. An attractive feature of the proposed model is the allowance for heterogeneity in risk among those individuals experiencing the event of interest in addition to the incorporation of a cured component. Maximum likelihood estimates can be obtained using the Expectation Maximization algorithm and standard errors are calculated from the Bootstrap method. The model is applied to hospital readmission data among colorectal cancer patients. (Β© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


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