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A formal total synthesis of PGA2 using the directed Pauson-Khand reaction

โœ Scribed by Marie E. Krafft; Colin Wright


Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
157 KB
Volume
33
Category
Article
ISSN
0040-4039

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A total synthesis of (-)-ฮฑ-kainic acid b
โœ Yoo Sung-eun; Lee Sang-Hee; Jeong Nakcheol; Cho Inho ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 231 KB

A total synthetic route to (-)a-kainic acid has been developed based on the Pauson-Khand reaction as a key reaction for the construction of the bicycle ring system. The unique structure and novel biological activities (anthehninticl, insecticidal\* and neuroexitatory activity) of kainic acid l, iso