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A formal total synthesis of (-)-isoavenaciolide

โœ Scribed by Chriss E McDonald; Robert W Dugger


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
193 KB
Volume
29
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


Total synthesis of (ยฑ)-isoavenaciolide a
โœ Steven D. Burke; Gregory J. Pacofsky; Anthony D. Piscopio ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 304 KB

The antifungal mold metabolites isoavenaciolide (1 b) and avenaciolide (1~) have been synthesized in racemic form from a common precursor, a-methylene lactone 4. obtained via a glycolate ester enolate Claisen rearrangement. We recently reported2 a total synthesis of the bislactone mold metabolite e