A fly's eye view of Huntington's disease
โ Scribed by Mitchell, Alison
- Book ID
- 109710868
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 101 KB
- Volume
- 395
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/27543
No coin nor oath required. For personal study only.
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After the discovery of genetic markers closely linked t o the gene for Huntington disease (HD) on chromosome 4 [Gusella et al., 19831, several centers in the U.S. and elsewhere began to offer a presymptomatic test for individuals at risk for this disorder. Since the mid-198O's, more than 1,000 perso
## Abstract Intrastriatal transplantation of striatal neuroblasts from human fetuses is a promising approach for treatment of Huntington's disease, on the basis of many experimental animal studies and, most recently, pilot clinical trials. Technically, several issues remain to be resolved (e.g., th