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A fluorogenic method for the demonstration of human serum 5′-nucleotide phosphodiesterase isozymes after polyacrylamide gel electrophoresis

✍ Scribed by K.W. Lo; S. Aoyagi; K.C. Tsou


Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
687 KB
Volume
117
Category
Article
ISSN
0003-2697

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✦ Synopsis


A rapid fluorogenic method for the demonstration of S-nucleotide phosphodiesterase in human serum has been developed. This method uses the substrate 4-methylumbelliferyl Sthymidylate impregnated in agarose gels or filter paper strips. Zymograms are developed in less than 30 min at 25°C. and the sensitivity of this method has been compared with that of the indigogenic method.