A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pKa and binding affinity and evidence for intermolecular C?F?CN interactions

✍ Scribed by Olsen, Jacob; Seiler, Paul; Wagner, Bj�rn; Fischer, Holger; Tschopp, Thomas; Obst-Sander, Ulrike; Banner, David W.; Kansy, Manfred; M�ller, Klaus; Diederich, Fran�ois

• Book ID: 120014104
• Publisher: Royal Society of Chemistry
• Year: 2004
• Tongue: English
• Weight: 572 KB
• Volume: 2
• Category: Article
• ISSN: 1477-0520
• DOI: 10.1039/B402515F