A flow cytometric procedure to measure functional LDL receptors for diagnosis of familial hypecholesterolemia

Flow cytometric assessment of LDL recept

Flow cytometric assessment of LDL receptor activity in peripheral blood mononuclear cells compared to gene mutation detection in diagnosis of heterozygous familial hypercholesterolemia

✍ Bent Raungaard; Finn Heath; Jens Uffe Brorholt-Petersen; Henrik Kjærulf Jensen; 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 88 KB 👁 2 views

## Background: Studies indicate that human peripheral blood mononuclear cells mirror low-density lipoprotein (ldl) receptor activity of other cells in the body. to measure ldl receptor activity in patients with heterozygous familial hypercholesterolemia (fh), we prepared peripheral blood mononuclea