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A Flexible Approach to 6,5-Benzannulated Spiroketals

โœ Scribed by Zoe E. Wilson; Jonathan G. Hubert; Margaret A. Brimble


Book ID
102831402
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
610 KB
Volume
2011
Category
Article
ISSN
1434-193X

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โœฆ Synopsis


Abstract

A novel route to simple 6,5โ€benzannulated spiroketal analogues has been developed. A convergent Hornerโ€“Wadsworthโ€“Emmons olefination enabled ready assembly of the spiroketal precursors. Use of a benzyl protecting group strategy enabled an efficient oneโ€pot hydrogenation/deprotection/spiroketalisation process to be employed providing a robust method to access a range of substituted aromatic monobenzannulated spiroketals.


๐Ÿ“œ SIMILAR VOLUMES


ChemInform Abstract: A Flexible Approach
โœ Zoe E. Wilson; Jonathan G. Hubert; Margaret A. Brimble ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons โš– 39 KB ๐Ÿ‘ 1 views

## Abstract The benzannulated spiroketal cores (IV) of berkelic acid are readily produced by Hornerโ€”Wadsworthโ€”Emmons olefination and a oneโ€pot hydrogenation/deprotection/cyclization process.

ChemInform Abstract: An Approach to Benz
โœ Christopher D. Bray ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons โš– 27 KB ๐Ÿ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โ€œFull Textโ€ option. The original article is trackable v