A five year prospective study of rheumatoid factor tests in juvenile rheumatoid arthritis
β Scribed by James T. Cassidy; Hans A. Valkenburg
- Publisher
- John Wiley and Sons
- Year
- 1967
- Tongue
- English
- Weight
- 575 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0004-3591
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Nineteen selected patients with severe, mostly systemic onset, juvenile rheumatoid arthritis were treated with methotrexate (MTX) for an average of 10.5 months. Twelve patients showed statistically significant improvement, as measured by the number of affected, swollen, tender, and functionally impa
## Abstract Hidden 19S IgM rheumatoid factors (RF)βi.e., RF detected in the IgMβcontaining fraction after separation of the serum at an acid pHβhave been found in 68% of patients with seronegative juvenile rheumatoid arthritis (JRA). Inhibition studies utilizing a hemolytic assay for RF were perfor