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A fission yeast strain expressing human CDC25A phosphatase: a tool for selectivity studies of pharmacological inhibitors of CDC25

✍ Scribed by Odile Mondesert; Matthieu Lemaire; Marie-Christine Brezak; MarieOdile Galera-Contour; Grégoire Prevost; Bernard Ducommun; Béatrix Bugler

Publisher
Springer-Verlag
Year
2004
Tongue
English
Weight
351 KB
Volume
45
Category
Article
ISSN
0172-8083

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## Abstract CDC25 phosphatases are key actors in cyclin‐dependent kinases activation whose role is essential at various stages of the cell cycle. CDC25 expression is upregulated in a number of human cancers. CDC25 phosphatases are therefore thought to represent promising novel targets in cancer the