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A fermentation strategy for production of recombinant protein subjected to plasmid instability

✍ Scribed by Shu-Jen Chen; Bo-Shun Ke; I-Chung Chiu

Book ID
107514004
Publisher
Springer US
Year
2008
Tongue
English
Weight
327 KB
Volume
25
Category
Article
ISSN
0256-1115

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A novel feeding strategy in fedbatch recombinant yeast fermentation was developed to achieve high plasmid stability and protein productivity for fermentation using low-cost rich (non-selective) media. In batch fermentations with a recombinant yeast, Saccharomyces cerevisiae, which carried the plasmi