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A family-based study of common polygenic variation and risk of schizophrenia

✍ Scribed by Ruderfer, D M; Kirov, G; Chambert, K; Moran, J L; Owen, M J; O'Donovan, M C; Sklar, P; Purcell, S M

Book ID
109890234
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
157 KB
Volume
16
Category
Article
ISSN
1359-4184

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Schizophrenia is a severe mental disorder with a lifetime risk of about 1%, characterized by hallucinations, delusions and cognitive deficits, with heritability estimated at up to 80% 1,2 . We performed a genome-wide association study of 3,322 European individuals with schizophrenia and 3,587 contro