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A Family-Based Analysis of Whether the Functional Promoter Alleles of the Serotonin Transporter Gene HTT Affect the Risk for Alcohol Dependence

✍ Scribed by Howard J. Edenberg; Jennifer Reynolds; Daniel L Koller; Henri Begleiter; Kathleen K. Bucholz; P. Michael Conneally; Raymond Crowe; Alison Goate; Victor Hesselbrock; T.-K. Li; John I. Numberger Jr.; Bernice Porjesz; Theodore Reich; John P. Rice; Marc Schuckit; Jay A. Tischfield; Tatiana Foroud


Book ID
109120009
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
675 KB
Volume
22
Category
Article
ISSN
0145-6008

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Analysis of a novel functional polymorph
✍ de Oliveira, JoοΏ½o R. Mendes; Otto, Paulo A.; Vallada, Homero; Lauriano, ValοΏ½ria; πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 11 KB πŸ‘ 2 views

It has been suggested that the serotonin transporter (5-hydroxytryptamine-transporter or 5-HTT) may be involved in the pathogenesis of affective disorders. Recently, Collier et al. (1996) found that the frequency of the low-activity short variant (s) of the 5-HTT-linked polymorphic region (5-HTTLPR)