APC mutation in the alternatively splice
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Rob B. Luijt; Hans F. A. Vasen; Carli M. J. Tops; Cor Breukel; Riccardo Fodde; P
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Article
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1995
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Springer
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English
β 1007 KB
Germ-line mutations in the adenomatous polyposis coli (APC) gene are responsible for familial adenomatous polyposis (FAP). Genotype-phenotype correlation studies in patients with FAP have demonstrated associations of certain variants of the disease with mutations at specific sites within the APC gen