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A Facile Synthetic Approach to 7-Deazaguanine Nucleosides via a Boc Protection Strategy

โœ Scribed by Wang, Ruo-Wen; Gold, Barry


Book ID
125899148
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
303 KB
Volume
11
Category
Article
ISSN
1523-7060

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In this paper we report on the development of a flexible and efficient synthetic approach towards 6,7-didehydrocarnosoic acid type analogues. The elaboration of the required trans-decalin system, the installation of the carboxylic acid in the angular position as well as the generation of the C 6 -C