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A facile synthesis of ring-fused alkylidenecyclopropanes by olefination reaction of bicyclo[n.1.0]alkanone N,O-hemiacetals with Wittig reagents

โœ Scribed by Morshed Alam Chowdhury; Hisanori Senboku; Masao Tokuda; Yuzuru Masuda; Toshiro Chiba


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
72 KB
Volume
42
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Ring-fused alkylidenecyclopropanes, bicyclo[n.1.0]alkylidene derivatives, were readily synthesized by olefination reaction of bicyclo[n.1.0]alkanone N,O-hemiacetals with Wittig reagents in good yields.


๐Ÿ“œ SIMILAR VOLUMES


A new synthesis of ring-fused alkylidene
โœ Morshed Alam Chowdhury; Hisanori Senboku; Masao Tokuda ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 98 KB

Bicyclo[n.1.0]alkylidene derivatives (ring-fused alkylidenecyclopropanes) reacted with diazomethane to give spiro-pyrazolines regioselectively. Thermal decomposition of spiro-pyrazolines resulted in ring-enlargement and afforded ring-fused alkylidenecyclobutanes (bicyclo[n.2.0]alkylidene derivatives