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A facile synthesis of optically active lactones using benzyl-3,6-anhydro glucofuranoside as chiral auxiliary

✍ Scribed by Vijay Nair; Jaya Prabhakaran; Tesmol G. George


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
485 KB
Volume
53
Category
Article
ISSN
0040-4020

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✦ Synopsis


A highly enantioselective synthesis OfT-and ~-lactones using an anhydrofuranoside derived from D-glucose as chiral auxiliary is described.


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An Efficient Synthesis of Optically Acti
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## Abstract An efficient enantioselective synthesis of 3‐acetoxy __trans__‐__Ξ²__‐lactams **7a** and **7b** __via__ [2+2] cycloaddition reactions of imines **4a** and **4b**, derived from a polycyclic aromatic amine and bicyclic chiral acid obtained from (+)‐car‐3‐ene, is described. The cycloadditio