A facile synthesis of N-benzyl-4-acetylproline via a tandem cationic aza-Cope rearrangement-Mannich reaction
β Scribed by Andrew Cooke; Jonathan Bennett; Emma McDaid
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 119 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Key steps in this approach to umaryllidaceae alkaloids containing oxidation at the R-position of the pyrroline ring are (a) copper(H)-promoted rearrangement of aminocyclopentanol 11 to afford the 3-silylhydroindole 12, and (b) oxidation of 12 by the general procedures of Kumada and Fleming to give t
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