A facile synthesis of indolo[3,2,1-jk]carbazoles via palladium-catalyzed intramolecular cyclization
β Scribed by Jun Lv; Qiancai Liu; Jie Tang; Franc Perdih; Kristof Kranjc
- Book ID
- 116909782
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- French
- Weight
- 858 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract The title compounds (IV) and (VII) are easily prepared by alkylation of appropriate carbazoleβtype precursors with oβbromobenzyl bromide and following Pdβcatalyzed cyclization.
Catalytic amounts of Pd(OAc)2 in the presence of c-Bu4NC1, OMF and an appropriate Et3N) cyclize nitrogen-containing o-lodoaryl alkenes to indoles, quinolines, isoquinolines and isoquTnolones in short reaction times, under mild temperatures, and in high yields. Transition metal reagents have proven h