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A Facile Synthesis of Dragmacidin B and 2,5-Bis(6‘-bromo-3‘-indolyl)piperazine

✍ Scribed by Miyake, Fumiko Y.; Yakushijin, Kenichi; Horne, David A.

Book ID
120229579
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
37 KB
Volume
2
Category
Article
ISSN
1523-7060

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✍ Tomomi Kawasaki; Kohsuke Ohno; Hidetaka Enoki; Yasuko Umemoto; Masanori Sakamoto 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 104 KB

The syntheses of trans-and cis-isomers of dragmacidin C and 3,4-dihydrohamacanthin A, and dragmacidin B have been accomplished by condensation of two indolylglycines followed by cyclization and reduction. The relative stereochemistry of dragmacidin C was confirmed to be cis, which is distinct from t