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A facile synthesis of 5-methylene-1,3-cyclohexadienes (o-isotoluenes) and 1,2,4,6-heptatetraenes

✍ Scribed by Andemichael, Yemane W.; Wang, Kung K.


Book ID
127020364
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
397 KB
Volume
57
Category
Article
ISSN
0022-3263

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Treatment of 5-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione with primary arylamines in CH 2 Cl 2 at rt gave 5-[(arylamino)(cyano)methylene]-2,2-dimethyl-1,3-dioxane-4,6-diones in excellent yields. The latter compounds were utilized for the preparation of 2-cyano-4-quino