A facile synthesis of 3-unsubstituted 4-isoxazolines
โ Scribed by Heung Bae Jeon; Kyongtae Kim
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- French
- Weight
- 175 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
Abstmc Treatments of 3-akylthio-S-aryl-2-~~um halides with sodium bomb&i& in a mixtmofethandandchlarofolmat-73c~tbecanepondine3-uMubstiMed4-~h exdentyields. Recently 4-isoxazdhes have meived codkrable attention paztly because of the mechenistic intacsta m tl&thexmal~onsdpoten~innewsyn~methotlfarhetaoatam c=nmds'.Ma nmberof4-isaxawlifieshavekenfoundintbe~theyh variousmlbstituaIt8at2,3,~md/a 5-po!&i~k&Imol&tbesyntlletkmethodsleparkdmiglltnotbeutilized~thesyntbP.sisof j-~rl-~~ot~~dpmga~~.Weaeawarrdmbr one iepolt far the spntbesis of 3-rmwrbstiMed Cl-m=
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A simple synthesis of the 3(2H)-furanone ring system is described. The 3(2H)-furanone moeity is a central structural unit in a growing number of natural products including simple compounds such as bullatenone and geiparvarin and more complex compounds such as jatrophone, the eremantholides, and lyc