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A facile synthesis of 1,3,4-selenadiazolo[2,3-b]quinazoline derivatives via japp-klingemann reaction

✍ Scribed by Abdou O. Abdelhamid; Hamdi M. Hassaneen; Ahmad S. Shawali

Book ID
112127117
Publisher
Journal of Heterocyclic Chemistry
Year
1983
Tongue
English
Weight
178 KB
Volume
20
Category
Article
ISSN
0022-152X

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A facile one-pot regioselective synthesi
A facile one-pot regioselective synthesis of [1,2,4]triazolo[4,3-a]5(1H)-pyrimidinones via tandem Japp–Klingemann, Smiles rearrangement, and cyclization reactions
✍ Ahmad S. Shawali; Magda A. Abdallah; Mosselhi A. N. Mosselhi; Thoraya A. Farghal πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 137 KB

## Abstract Coupling of active [(4‐oxo‐6‐phenyl‐3__H__‐pyrimidin‐2‐yl)thio]methine compounds (**3**) with diazotized anilines in the presence of base gave [1,2,4]triazolo[4,3‐a]pyrimidines (**7**). The latter products were also obtained by reactions of hydrazonoyl chlorides (**10**) with either 6‐p