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A facile synthesis of 1-hydroxy-2- phosphonocyclobutenedione

✍ Scribed by Choung Un Kim; Peter F. Misco


Book ID
103403874
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
139 KB
Volume
33
Category
Article
ISSN
0040-4039

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## Abstract Ethyl 2‐(chloromethyl)‐2‐hydroxy‐2__H__‐chromene‐3‐carboxylates **2a**–**2j** have been synthesized by reaction of substituted salicylaldehydes with ethyl 4‐chloro‐3‐oxobutanoate, in the presence of piperidine in CH~2~Cl~2~ at room temperature, in good yields.