A facile one-pot synthesis of thioethers using heteropoly acids
β Scribed by Ajeet Kumar; Prashant Singh; Santosh Kumar; Ramesh Chandra; Subho Mozumdar
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 536 KB
- Volume
- 276
- Category
- Article
- ISSN
- 1381-1169
No coin nor oath required. For personal study only.
β¦ Synopsis
A convenient one-pot synthetic method for the formation of thioethers from various aryl/alkyl halides using heteropoly acid, is described. Heteropoly acid is a simple, cheap and robust catalyst that couples a broad range of electron-deficient as well as electron-rich substrates in excellent yields in short time.
π SIMILAR VOLUMES
Synthesis of the title compounds from (2-trifluoromethyl)phenylacetonitrile is described. The mechanism of the reaction is believed to involve the formation of the quinone methide intermediate.
## Abstract A facile oneβpot synthesis of oxazoles 1aβh is described that utilizes readily available aromatic Ξ±βmethyl ketones and a safe hypervalent iodine reagent, iodobenzene diacetate.