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A facile one-pot synthesis of novel substituted 1,2,3,4-tetrahydropyrimidines Part 5 : Synthesis of bis[(l-alkyl/aralkyl)-5-benzoyl-6-methylthio-1,2,3,4-tetrahydropyrimidinyl]alkane and benzene, bis[3-phenyl-7-methyl-4,5,6,7-tetrahydropyrazolo[3,4-d]-pyrimidinyl]alkane and bis[1-benzyl-7-phenyl-1,2,3,4-tetrahydro-pyrazolo[1,5-a]triazinyl]alkane and benzene

✍ Scribed by Milan Ch. Dutta; Kaushik Chanda; Jai N. Vishwakarma; Philippe Helissey


Publisher
Journal of Heterocyclic Chemistry
Year
2005
Tongue
English
Weight
70 KB
Volume
42
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

Bis‐1,2,3,4‐tetrahydropyrimidinylalkanes/benzenes 2a‐f have been synthesized by the reaction of N,S‐acetals with formaldehyde and diamines. Reaction of pyrazoles 3a and 3b with diamines and formaldehyde yield bis‐4,5,6,7‐tetrahydropyrazolo[3,4‐d]pyrimidinylalkanes 4a‐b and bis‐1,2,3,4‐tetrahydropyrazolo[1,5‐a]triazinylalkanes and benzene 5a‐c respectively in good yields.


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