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A Facile Method To Transform trans -4-Carboxy-3,4-dihydro-3-phenyl- 1( 2H )-isoquinolones to Indeno[1,2- c ]isoquinolines

✍ Scribed by Xiao, Xiangshu; Cushman, Mark


Book ID
126180994
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
120 KB
Volume
70
Category
Article
ISSN
0022-3263

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A new procedure for the synthesis of 2,3-diaryl-3,4-dihydro-4-hydroxy-1(2H)isoquinolones is described rn which the cis-isomer predominates. Dehydration leads to 2,4-diarylisocarbostyrils. The synthetic utility of metallated phthalide derivatives has recently received considerable attention for the