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A Facile High Yielding Method for Synthesis of N-Alkyl-4-Nitroimidazoles

โœ Scribed by Bhujanga Rao, A. K. S.; Gundu Rao, C.; Singh, B. B.


Book ID
121274993
Publisher
Taylor and Francis Group
Year
1991
Tongue
English
Weight
194 KB
Volume
21
Category
Article
ISSN
0039-7911

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A facile method for the N-alkylation of
โœ W. Russell Bowman; Daniel R. Coghlan ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 853 KB

Monoalkylation of the a-amino group of or-amino acid derivatives can be facilitated using 2and 4-nitrophenylsulfonamide intermediates. The nitrophenylsulfonamides of a-amino esters can be alkylated using an equimolar amount of carbonate base and a variety of alkyl bromides. Ready removal of the nitr